Sis, we're sure you've seen the ingredient PDRN (or polynucleotides) on skincare products — the latest K-beauty innovation for skin regeneration and anti-aging — but is it really worth the hype? 🤔

This ingredient can be found in nearly all of the most popular Korean skincare products. Our girls have prepared a quick guide for you on the benefits of PDRN skincare, why it became so popular, the types of polynucleotides, and the best products with this ingredient you should try 🤩

What is PDRN?

PDRN (Polydeoxyribonucleotide) is a DNA fragment derived from salmon sperm (reproductive cells of the male fish). This ingredient activates the skin’s natural regeneration processes that tend to "go to sleep" due to aging or stress. In product ingredient lists, you’ll often find it labeled as Sodium DNA.

The importance of PDRN in skincare is significant — and there’s real science behind it. Before making its way into the beauty world, PDRN was already being used in medical treatments for wound healing and skin regeneration. Doctors used it for treating burns, scars, and even post-surgery recovery. So, despite its unusual origin, it has strong backing both in medicine and skincare. It's especially ideal for sensitive, mature, and problematic skin 🤗

Benefits of PDRN in Korean skincare

PDRN in skincare products can be derived from either salmon DNA or plant-based sources, so every sister can find the perfect match for her needs and skincare style 💫

Salmon-based PDRN is the type of polynucleotide used in both salon treatments and at-home skincare. It has powerful regenerative properties — and here’s why it’s loved by so many:

1. Speeds up healing of wounds and micro-damage — clinical studies show up to 37.3% full tissue recovery
2. Stimulates collagen production, making the skin firmer.
3. Has anti-inflammatory effects, which is especially helpful for problematic skin.
4. Helps with acne and post-acne, improving the overall condition of the skin barrier.

Important! If you're allergic to fish or seafood, be sure to check the ingredient list carefully. Always do a patch test before starting regular use of a PDRN product — safety first ❤️

Plant-based PDRN – a gentle alternative for sensitive skin

This is a newcomer in the K-beauty world, but it has already won over those seeking vegan or hypoallergenic formulas. Plant-based PDRN is:

1. Safe for very sensitive and reactive skin.
2. Has soothing and anti-inflammatory effects.
3. Suitable for daily skincare, perfect when you just want to glow for no reason ✨

Korean skincare with PDRN works wonderfully for problematic and aging skin, and also helps to restore the skin's hydro-lipid barrier after just a few uses.

What’s more, the effect of polynucleotides is cumulative, so you’ll be able to enjoy radiant, healthy skin for a long time ⏰

Best Korean skincare products with PDRN

The best PDRN-based skincare products combine the power of polynucleotides with soothing ingredients tailored to your skin type and current needs — from deep hydration to recovery after stress or irritation ✨

Toners and essences with PDRN deeply hydrate, promote skin repair, and improve elasticity through the regenerative power of polynucleotides.

Serums and ampoules with PDRN — to be used after toner and before cream — are great for restoring the skin barrier, hydrating, and smoothing fine lines from within.

Sheet masks with polynucleotides provide intensive hydration, calming, and regeneration, while improving elasticity.

Creams with PDRN strengthen the skin barrier, deeply moisturize, and promote regeneration, improving texture and firmness.

All of these products work to slow down signs of aging, smooth out skin texture, and give your face a firm and glowing look ✨

Our girls also recommend trying a PDRN-based primer — it helps protect your skin from external aggressors (UV rays, heat), tightens pores, makes them less visible, and improves skin texture 💪

PDRN-based products are truly amazing! But just like with any skincare, listen to yourself, patch test new products carefully, and don’t hesitate to ask your dermatologist for advice. Your skin is unique — give it exactly what it needs 💖

If you're dreaming of glowing skin with no filters — maybe it’s time to get to know PDRN up close 😉